Mental Health News

2011-02-09 / Mental Health / No Comment

ADHD Often Linked to Other Mental Health Disorders

Children with attention deficit/hyperactivity disorder are more likely to have other mental health or neurodevelopmental conditions, and their social and educational functions worsen with more comorbidities, according to a study published online Feb. 7 in Pediatrics.

TUESDAY, Feb. 8 (HealthDay News) — Children with attention deficit/hyperactivity disorder (ADHD) are more likely to have other mental health or neurodevelopmental conditions, and their social and educational functions worsen with more comorbidities, according to a study published online Feb. 7 in Pediatrics.

Kandyce Larson, Ph.D., of the UCLA Center for Healthier Children, Families, and Communities in Los Angeles, and colleagues examined the patterns of comorbidity, functioning, and service use for 5,028 children with ADHD. They performed a cross-sectional analysis using data from the U.S. 2007 National Survey of Children’s Health.

The researchers found a parent-reported prevalence of ADHD of 8.2 percent. Children with ADHD were significantly more likely to have a learning disability, conduct disorder, anxiety, depression, and speech problems compared to children without ADHD. Children with ADHD were also more likely to have difficulty in school and socially. They also had higher odds of having poor parent-child communication and higher levels of parent aggravation. Most children with ADHD had at least one comorbidity, and poor children were 3.8 times more likely to have three or more comorbidities than well-off children. As the number of comorbidities increased, the children’s function declined and the use of health and educational services increased.

“Professionals and parents need to be aware of the high prevalence of mental health/neurodevelopmental comorbidities among school-aged children with ADHD in the United States. Patterns of worsening function with increasing numbers of comorbidities reflect the challenge of meeting the needs of children with complex clinical pictures within the current system of care,” the authors write.

Smoking pot speeds mental illness

CANNABIS can speed up the appearance of psychotic illness, a ground-breaking Australian study has found .
Dr Matthew Large, a staff specialist in mental health from the University of New South Wales and the Prince of Wales Hospital, said the risks are especially high for younger people, whose brains are still developing.

“What our research has found is that cannabis smoking brings schizophrenia on early by an average of 2.7 years,” he said.

For young people who smoke cannabis regularly, instead of having about a 1% chance of developing schizophrenia during their lifetime, they would end up with something like a 5% chance of developing schizophrenia, said Dr Large.

His research, that pulled together data on 20,000 patients and drew on more than 80 international studies, is published in the journal Archives of General Psychiatry.

The study has again prompted drug experts to call for regulation, not prohibition, of marijuana.

With about 33% of the Australian population and 18% of secondary school students using the drug, in a few years there would be more Australians smoking cannabis than smoking tobacco, said Dr Alex Wodak, the director of the Alcohol and Drug Service at Sydney’s St Vincent’s Hospital and head of the Australian Drug Law Reform Foundation.

“Having a black market of that size is not good for anybody,” he said.

“An unregulated cannabis market is about profits, not ethics. We have a responsibility to reduce the harm associated with cannabis use.”

He recently said he believed the time was right for a trial of a hash coffee shop in the community of Nimbin.

David Halliwell, a Fellow of the Chapter of Addictive Medicine Unit at the Royal Australasian College of Physicians and a long-term Northern Rivers resident said: “At the moment, the cannabis industry is just kept in the dark and prohibited.

“The laws have failed.

“We have an illegal market run by criminals. Regulating supply would be a much better way (of controlling cannabis use).”

South Carleton High School Does it for Daron

Summary: South Carleton High School is awash in the colour of purple today to draw attention to youth depression and mental illness in general in honour of Daron Richardson.

South Carleton High School is awash in the colour of purple today to draw attention to youth depression and mental illness in general in honour of Daron Richardson.

School Principal Trudy Garland says students Cydney Roesler, Rebecca Watson, Paige Watson, Logan Watson, Megan Carty, Mackenzie Coney, and Hannah Driver are selling wrist bands to raise funds for the Daron Richardson Foundation partnered with the Royal Ottawa for Mental Health. Meanwhile Manager of Cafeteria Services Kelly Watson baked cookies and cupcakes with purple sprinkles and the slushie machine is purple in honour of this special day.

Daron’s 15th birthday would have been celebrated today. February 8, 2011 has now been dubbed Do It For Daron Purple Pledge Day, where people are being asked to wear purple in support of the Daron Richardson Fund at the Royal Ottawa Foundation for Mental Health. Purple was Daron’s favourite colour.

The Royal Ottawa Foundation hopes the movement will help youth address any problems they may be experiencing. The funds will go towards an early identification and intervention program for youth.

Ms. Garland says the students involved in the South Carleton High School project played in community hockey games with Daron over the years and wanted to participate in honouring her memory. She added, “They believe it is important to bring awareness regarding mental health to youth and who better to do it, but youth themselves. Kids talk to kids and they listen.”

South Carleton High School is located at 3673 McBean Street in Richmond.

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Vision Care Today

2011-02-08 / Health News / No Comment

Wendy discovers vision care with flair!

As caring parents, our children’s health is of utmost importance. We are very diligent about getting our children to the family doctor, dentist and optometrist for annual checkups, but often neglect our own health in the process.

Self-care is something no parents should ignore. By maintaining their own health and wellness, they are better able to care for their children. At the same time, they’re setting an excellent example for their children to follow later in life.

Through the Beautiful You lifestyle makeover program, Wendy Korchinski is learning the importance of self-care.

Comprehensive vision care is an important element of the Beautiful You program, provided by Family Focus Eyecare, located at #1 – 419 Ludlow Street in University Heights, adjacent to Willowgrove.

Family Focus Eyecare was established in 1998 by Dr. Elisabeth Foucault and Dr. Nadia Lypka. Dr. Ken Lypka joined the practice in 2002. The practice has continued to grow with Saskatoon, welcoming associate optometrists Dr. Jen Bachiu, Dr. Vy Pham, Dr. David Sherin and Dr. Fern Yee, who provides vision therapy services. The expert optometrists, along with their friendly support staff, are dedicated to providing patients with the utmost in vision care.

Wendy was pleased to learn that she would be working with Dr. Nadia Lypka at Family Focus Eyecare, as she was very familiar with the practice. This is where she has taken her three children for their vision care for the past four years. During that time, however, Wendy had neglected to have her own eyes examined. “I tend to not put myself on the list,” says Wendy.

With a history of both glaucoma and macular degeneration in Wendy’s family, Dr. Lypka says it is vital for Wendy to have a comprehensive eye exam every two years.

“Macular degeneration and glaucoma are two of the leading causes of blindness among Canadians. When there is a family history of this, it’s even more important for patients to be diligent about having regular eye examinations. With glaucoma, symptoms often aren’t apparent until the advanced stages. At that point, damage is irreversible. Through a routine eye exam, we can detect the early signs of these eye diseases, and other potential health problems, and ensure prompt treatment,” says Dr. Lypka.

Family Focus Eyecare employs the newest technologies to provide the ultimate in patient care, including a new imaging technique called the Optical Coherence Tomography (OCT) which provides unprecedented high resolution cross-sectional images of structures in the back of the eye. “The OCT is very helpful in earlier diagnoses of glaucoma and retinal problems,” says Dr. Lypka. “We were pleased that Wendy’s eyes are very healthy.”

Dr. Lypka’s exam revealed that in addition to being near-sighted, Wendy had presbyopia, a common eye condition that begins to develop in your 40s. Presbyopia is the diminished ability to focus on near objects.

“I was asking the kids to read words in small print to me. My arms just weren’t stretching long enough any more!” says Wendy.

Wendy also has a common eye condition called astigmatism, which means the front surface of the eye is shaped like a football, rather than a perfect sphere. “Astigmatism can distort your vision, up-close and in the distance,” says Dr. Lypka.

Dr. Lypka prescribed premium progressive lenses. “The lenses not only correct her distance vision, they now correct her near vision as well.”

Optometric assistant Tracy Sielski helped Wendy select stylish new frames for her lenses, by J.F. Rey, designed and made in France.

Family Focus Eyewear offers a vast selection of fashionable frames. Among the collection of over 1,500 frames are trendy designer lines including Lafont, Orr Green, Versace, Cogan and Fendi.

“I chose the J.F. Rey frames for Wendy because they best flattered the shape of her face and her skin tones. The trendy style has really updated Wendy’s look!” says Tracy.

“I really like them! They’re fashion-forward but they still go with everything I wear,” says Wendy.

It had been over 15 years since Wendy had last worn contact lenses. “I didn’t find them that comfortable, and after my first son was born, it was just easier to throw on my glasses,” says Wendy.

New advances in technology have greatly increased comfort levels and made it possible for people with both astigmatism and presbyopia to enjoy the freedom of contact lenses.

“We are in the process of fitting Wendy with contact lenses. She requires a Toric contact lens for her astigmatism. Because she’s also presbyopic, she also requires a multi-focal lens which create multiple levels of corrective powers. It can take a few adjustments to find the lenses that will stabilize the best. Wendy’s now trying her second pair of lenses,” says Dr. Lypka.

“I really enjoy the freedom of wearing contact lenses, especially when I’m working out at the gym,” says Wendy.

Next, Family Focus Eyecare will provide Wendy with a pair of glamorous designer sunglasses. Over 300 styles of designer sunglasses are on display in the Sunglass Cove at Family Focus Eyecare, including the latest looks by Prada, Coach, Michael Kors, Jimmy Choo, Ed Hardy, Gucci and Versace. “We also feature premium sunglass lines by Oakley, Kaenon and Maui Jim,” says Tracy.

Sunglasses are more than just a fabulous fashion accessory. They provide vital protection from the sun’s damaging UV rays, says Dr. Lypka. “UV radiation can contribute to cataracts and macular degeneration, and we already know that Wendy has a family history of macular degeneration. Wearing sunglasses also helps protect the delicate skin around the eyes, not only from wrinkles, but also from skin cancer. This is an area of the face where skin cancer commonly occurs.”

Working with Wendy has been a delight for everyone at Family Focus Eyecare, says Dr. Lypka. “She’s very bubbly and has a great attitude! She’s taking the Beautiful You program very seriously and her hard work shows!”

“I love going to Family Focus Eyecare. Dr. Lypka and the staff are so friendly and caring. It’s nice that I’ll be going there now, as well as my kids!” says Wendy.

Elka Nir Joins VisionCare Board of Directors

Head of Life Sciences at Giza Venture Capital brings twenty years of experience leading dynamic and cutting edge technology organizations

SARATOGA, Calif., Feb. 5, 2011 /PRNewswire/ — VisionCare Ophthalmic Technologies, Inc., a developer of advanced visual prosthetic devices for the treatment of end-stage age-related macular degeneration, today announced Elka Nir of Giza Venture Capital has joined VisionCare’s Board of Directors. Ms. Nir expands the company’s Board to seven.

Ms. Nir heads the life sciences sector for Giza and serves on the board of directors of five medical device companies in Israel and the US. Prior to Giza, she led large multi-disciplinary teams (R&D, supply chain, quality & regulatory, marketing) at a division of Johnson & Johnson managing multi-million dollar budgets and delivering innovative market leading products, resulting in over $400 million in yearly revenues and double-digit annual growth.

Ms. Nir holds a B.Sc. in Computer Science, from Technion-Israel Institute of Technology, Haifa, Israel, a B.S. from the University of Haifa, and completed the Senior Executive Education program at Stanford University School of Business.

Allen W. Hill, VisionCare’s President and CEO, commented, “VisionCare welcomes Elka to our Board. She was instrumental in helping VisionCare raise $31.4 million in the recent Series E financing. Elka’s extensive experience in executive roles and raising funds for the development of new state of the art solutions, via business collaboration with global market leaders, will be of great assistance to VisionCare.”

On joining the VisionCare Board, Elka Nir commented, “VisionCare has made tremendous progress in developing, clinically testing, and obtaining FDA approval for its implantable telescope prosthesis in patients with advanced forms of macular degeneration, which disables hundreds of thousands of individuals in major markets. VisionCare’s products show significant promise of improving vision and quality of life for these individuals who now have no other surgical option. I am looking forward to working with the Board and the company as it begins US commercialization of this breakthrough product later this year.”

About the Telescope Implant

The Implantable Miniature Telescope (by Dr. Isaac Lipshitz) is designed to improve vision and quality of life in patients with end-stage AMD. Smaller than a pea, the telescope is implanted in one eye in an outpatient surgical procedure.

CentraSight Treatment Program

The first-of-kind telescope implant is integral to a new patient care program, CentraSight, for treating patients with end-stage AMD. The CentraSight treatment program involves a patient management process and access to reimbursement resources for patients and physicians.

About End-Stage Macular Degeneration

AMD is a disorder of the central retina, or macula, which is responsible for detailed vision that controls important functional visual activities like recognizing faces and watching television. The National Eye Institute estimates that over 1.7 million Americans over age 50 suffer vision loss from advanced AMD, which frequently culminates as end-stage AMD (visual impairment due to untreatable advanced AMD in both eyes). These patients often experience a loss of independence and quality of life, and have difficulty with activities of daily living. Approximately half of the individuals living with advanced AMD are affected in both eyes.

About Giza Venture Capital

Located in Tel Aviv, Giza is a leading venture capital firm investing in seed and early-stage technology companies. Giza currently manages five funds totaling $600 million. Founded in 1992, the firm’s professionals have extensive experience and expertise in life sciences, communications, semiconductor, information technology, enterprise software, clean tech, media, and entertainment sectors. Giza has invested in ninety-seven companies with thirty-two successful exits.

About VisionCare

VisionCare Ophthalmic Technologies, Inc., headquartered in Saratoga, CA, with facilities in Petah Tikva, Israel, is a privately-held company focused on the development, manufacturing, and marketing of implantable ophthalmic devices and technologies that are intended to significantly improve vision and quality of life for individuals with untreatable retinal disorders.

Reminder tool `helps majority of contact lens wearers

A tool used by contact lens wearers to remind them to put in or take out the products is effective in the vast majority of cases, it has been claimed.

Vistakon, a division of Johnson & Johnson Vision Care, claims that its Acuminder tool is rated as helpful by 95 pr cent of those who use it as part of their daily contact lens routine.

In addition, 66 per cent of the users polled in recent survey by the organisation say that it has helped them improve the frequency and accuracy of their contact lens replacement.

Acuminder was found to be particularly effective for two-weekly lens wearers, with 76 per cent remembering to change them after 14 days when using the reminder, compared with only 40 per cent who did not use the tool.

Recent contact lens safety advice was issued by consultant ophthalmologist Peter McDonnell, honorary treasurer at the Royal College of Ophthalmologists, who said that people who follow manufacturer instructions on lenses should not encounter any problems.

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Diabetes Treatment and Diagnosing

2011-02-05 / Diabetes / No Comment

Afe Babalola decries commercialisation of public health service

Pro-Chancellor, University of Lagos, Chief Afe Babalola, has criticised the commercialisation of public health service delivery, saying this has made government hospitals become more expensive than private ones.
Chief Babalola stated this at the opening of the first Strategies For Improving Diabetes Care In Nigeria (SIDCAIN) annual lecture entitled, “Health Scheme and National Development”.

According to the legal luminary,”it cannot be right that public health institutions, especially those set up by Federal Government with substantial subventions should become more expensive than their private counter parts.”

He stated: “there is abundant empirical evidence that commercialisation of public health service delivery exerts huge negative imparts on the attainment of the Millennium Development Goals in Nigeria.”

“I do not subscribe to making health care an avenue for profiteering. It is reported that, while an average private hospital in Ibadan where the UCH is located charges N500 for consultation, the UCH charges between N750 to N1, 250 for consultation alone.”

Chief Babalola declared further that, “these fees require urgent downward review, perhaps through a health scheme that would subsidise the costs.”

Earlier at the lecture, whose theme was “Diabetes mellitus in a developing country” Dr Sonny Kuku, Chairman, University College Hospital (UCH), declared that diabetes had reached an epidemic proportion.

He stated that currently the treatment and prevention of diabetes rely on education, diet and medications.

Evaluation of four novel genetic variants affecting hemoglobin A1c levels in a population-based type 2 diabetes cohort (the HUNT2 study)

Chronic hyperglycemia confers increased risk for long-term diabetes-associated complications and repeated hemoglobin A1c (HbA1c) measures are a widely used marker for glycemic control in diabetes treatment and follow-up. A recent genome-wide association study revealed four genetic loci, which were associated with HbA1c levels in adults with type 1 diabetes.

We aimed to evaluate the effect of these loci on glycemic control in type 2 diabetes.

Methods: We genotyped 1,486 subjects with type 2 diabetes from a Norwegian population-based cohort (HUNT2) for single-nucleotide polymorphisms (SNPs) located near the BNC2, SORCS1, GSC and WDR72 loci. Through regression models, we examined their effects on HbA1c and non-fasting glucose levels individually and in a combined genetic score model.

Results: No significant associations with HbA1c or glucose levels were found for the SORCS1, BNC2, GSC or WDR72 variants (all P-values >0.05).

Although the observed effects were non-significant and of much smaller magnitude than previously reported in type 1 diabetes, the SORCS1 risk variant showed a direction consistent with increased HbA1c and glucose levels, with an observed effect of 0.11% (P=0.13) and 0.13 mmol/l (P=0.43) increase per risk allele for HbA1c and glucose, respectively. In contrast, the WDR72 risk variant showed a borderline association with reduced HbA1c levels (beta=-0.21, P=0.06), and direction consistent with decreased glucose levels (beta=-0.29, P=0.29).

The allele count model gave no evidence for a relationship between increasing number of risk alleles and increasing HbA1c levels (beta=0.04, P=0.38).

Conclusions: The four recently reported SNPs affecting glycemic control in type 1 diabetes had no apparent effect on HbA1c in type 2 diabetes individually or by using a combined genetic score model. However, for the SORCS1 SNP, our findings do not rule out a possible relationship with HbA1c levels.

Hence, further studies in other populations are needed to elucidate whether these novel sequence variants, especially rs1358030 near the SORCS1 locus, affect glycemic control in type 2 diabetes.

Author: Jens HertelStefan JohanssonHelge RaederCarl PlatouKristian MidthjellKristian HveemAnders MolvenPal Njolstad
Credits/Source: BMC Medical Genetics 2011, 12:20

Hallmark Health to affiliate with Joslin Diabetes Center

The following was submitted by Hallmark Health:

According to the American Diabetes Association there are nearly 24 million children and adults in the United States living with diabetes and an additional 57 million Americans at risk for the disease.
In response to the epidemic of diabetes in men and women living in Massachusetts, Hallmark Health System, the leading provider of vital health services north of Boston, has joined forces with the Joslin Diabetes Center, the world’s preeminent diabetes research and clinical care organization.

The Joslin Diabetes Center Affiliate at Hallmark Health, which will be led by Sunita Schurgin, MD, Tara Hamilton, MD and Sybil Kramer, MD will offer some of the latest advances for treating diabetes and its complications as well as patient education and support services. Hallmark Health will be one of 40 national and two international Affiliate locations as well as the only Joslin Affiliate in Boston’s northern suburbs.

“We are honored to enter into this partnership with the Joslin Diabetes Center,” said Terry Giove, vice president of Ambulatory Services for Hallmark Health. “Our two organizations share the common goal of providing the very best in diabetes care. We look forward to working closely with Joslin to treat, educate and support diabetes patients throughout the Hallmark Health system.”

Joslin provides clinical, educational, operational and marketing support to its Affiliates to help assure that high quality, comprehensive and cost-effective diabetes care is available to each partner’s community — ensuring that these organizations and the patients they serve are in touch with some of the latest clinical trends and research breakthroughs.

“We are delighted to have Hallmark Health join us in the fight against diabetes,” said Janice Murphy, JD, director of National Affiliated Programs for the Joslin Diabetes Center. “We’ve got a huge problem with diabetes in the United States. Hallmark has shown its commitment to dealing with this chronic disease and we’re thrilled to partner with them.”

The Center at Hallmark Health will offer advanced clinical care for the treatment of diabetes for patients ages 18 and older, as well as patient education and support services. This multi-disciplinary program will offer services for:

• Diabetes screening
• Comprehensive diabetes care and management
• Complication screening, prevention and treatment
• Weight management and nutritional counseling
• Medication management
• Insulin pump management
• Self-care and self-management
• Gestational diabetes management

Patients will be cared for by a dedicated, highly experienced team including a board-certified endocrinologist, registered dietitian, certified diabetes educator and other medical and support professionals. Along with expert diabetes care, these physicians will continue to provide treatment for a wide variety of other endocrinology diagnoses.

Ipsen suffers blow as Roche drops diabetes deal

(Reuters) – Swiss drugmaker Roche has dropped development of diabetes treatment taspoglutide, ending its partnership with French drugmaker Ipsen and pushing Ipsen’s shares as much as 4 percent lower.

Ipsen said on Wednesday it would thoroughly assess the available data on the drug to see if it can be developed with another partner as it would be too costly to develop the drug, once seen to have $2 billion sales potential, on its own.

The announcement came at Ipsen’s 2010 sales presentation. Fourth-quarter sales rose 1.1 percent to 258 million euros ($360 million), leaving full-year sales up 6.5 percent to 1.03 billion. They were up 5.1 percent in constant currency terms.

Quarterly sales missed forecasts of some analysts due to weak performance in primary care and in the United States.

“On a geographical basis, at the exception of France, Europe did relatively well. As far as the U.S. franchise, it is again disappointing,” Rodolphe Besserve, analyst at Societe Generale wrote in a research note.

Ipsen also said the group would present a new strategy in the second quarter of this year as U.S. healthcare reforms and price cuts in Europe are dampening growth prospects for the industry overall.

“The healthcare industry now faces new challenges and is currently undergoing important changes worldwide,” said Chairman and Chief Executive Marc de Garidel who replaced Jean-Luc Belingard over strategic differences in November. “I have decided to run a thorough strategic review to further define Ipsen’s mid-and-long term vision,” he said in a statement.

Taspoglutide was licensed to Roche in 2006, having shown promising end-stage clinical trials.

But then the drug suffered setbacks in its development, and Roche suspended dosing in a late-stage trial in September, leading many analysts to believe it would be halted due to adverse reactions among some patients.

Societe Generale’s Besserve said it was unlikely that Ipsen could find another partner for taspoglutide which belongs to the same glucagon-like peptide (GLP-1) drug class as Novo Nordisk’s Victoza and Amylin Pharmaceuticals Inc’s and Eli Lilly and Co’s Byetta.

Another GLP-1 product, Bydureon, suffered a setback when Amylin Pharmaceuticals Inc’s and Eli Lilly and Co, citing the need for further studies, including the drug’s effect on heart rate.

“Following the disappointing setbacks for … taspoglutide, we see few near-term catalysts for Ipsen’s stock, Jefferies Research analyst Tara Shivarattan wrote in a note, citing the slow ramp-up of Ipsen’s U.S. business and a challenging environment in Europe.

Ipsen shares fell 4.3 percent to 24.44 euros by 1011 GMT.

The company will release its full-year results on March 2.

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Alternative Medicine News

Heart Disease: An Equal Opportunity Destroyer

Did you know Heart Disease kills 29,000 Americans every day? About one every 39 seconds!

“..Individuals with insulin resistance or diabetes in combination with one or more of risk factors ( poorly controlled blood sugars or out of normal range, high blood pressure, obesity, lack of physical activity, smoking and abnormal cholesterol ) are more likely to fall victim to heart disease or stroke..”

I know what you are thinking…” not me “…

My wake up call happened a few years ago when a functional medicine practitioner gave me the bad news.

I expressed my frustration to the doctor that I had a very difficult time losing weight. In 2008, I weigh 187 pounds and I wanted to lose at least 30 pounds. A weight that I thought I could maintain.

I had tried every pill popping supplement at GNC. I had tried the South beach diet, Atkins diet, blood type diet….every diet in the market, every diet book on weight loss….and, though I may have lost a few pounds initially, I would regain it back….quickly.

Today, most health professionals in a traditional medical practice do not address weight issues or obesity concerns. And very commonly pre-diabetes or weight control problems are not a commonly explored educational part of our training as general practitioners. Even then we are taught to follow the food pyramid nutrition protocol.
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Intuitively, I thought that I had a metabolic disorder that was causing me to have serious struggles losing weight. It was obvious that following the recommended food pyramid was not helping me reach my weight goals.

So, I went to see an Anti-aging Regenerative & functional medicine practitioner who ran a battery of preventative blood tests. These tests measure your hormonal imbalances, inflammatory markers and fasting insulin levels.

The results: my insulin fasting levels were high (>17) and my fasting blood sugars were> 90. A condition that placed me as a pre-diabetic or Insulin Resistance. My body fat: 48%. I had no other medical conditions. I was a young 34 years old, athletic, gym-goer….what was wrong?

I felt perfectly well. I never had to take any prescriptions for any chronic illness. In fact in our family because there is an overall concern for any of us developing diabetes my parents set a great example of living healthy. We all went to the gym six out of seven days, ate lean and green foods and even cut down on occasional wine drinking for fear that the excess calories could jeopardize our weight loss goals. We followed what we thought were common sense rules.

So it was without a doubt on that day when another doctor was telling me with a concerning tone that I was pre-diabetic I thought:” You can’t be serious “….” but I go the gym on a regular basis…I eat healthy…. ”

Doctor: “Do you have heart disease in your family?” (he asked)

Me: “Yes….We have Diabetes and heart conditions on both sides of my family “….” Both grandmothers, Grandfather, and now Aunt Kattia….”

Doctor: “You have high inflammatory markers as a result of your pre-diabetic state and your aerobic heart oxygen capabilities are suboptimal ”

And then it hit me like a tons of bricks….my years of being overweight had resulted in the gradual development of insulin resistance….and it was my inherent metabolic disorder of insulin resistance that had caused me to develop excess body fat and a virtual impossible journey to lose weight…”

It all made sense now. The reason it was challenging for me to lose weight was because I was Insulin Resistance. So that any starchy carbohydrates, processed foods or food allergens I consumed would cause a spike in my insulin. The daily spikes in insulin were the result of my pancreas working hard to normalize circulating blood sugars. Because my muscle and liver cells were inherently “resistant” to insulin (hence the name)…my body was in a state of glucose starvation.

So my pancreas worked harder and harder to produce more insulin in an effort for my muscle and liver cells to utilize the glucose it needed. This inherent resistance of major organ cells to utilize glucose would cause insulin to deposit the excess glucose in fat cells…And that perpetuated a vicious cycle….of high inflammation,damaged blood vessels, reduced aerobic heart capability, high insulin, starved cells, excess body fat, hunger cravings and….difficulty losing weight and heart disease”.

Did you know these particular tests are not commonly done at your local physician’s office? Instead, the common trend is to wait until your blood sugars are severally abnormal and for you to manifest symptoms of diabetes so that another set of tests are performed to confirm what is obvious….Diabetes.

As a result of my extensive fellowship training in the field of Anti-aging Regenerative & Functional Medicine, I have ended my struggle with weight loss. My insulin resistance is under control using medical foods and low glycemic meals. My body fat is now 30.8 %. I perform regular detoxification programs. I have no more hunger cravings or sugar addictions. I know now that my lifestyle habits of eating lean and green foods and exercising are now working for me, not against me, and that I can now focus on other ambitions and projects knowing that my health is optimum.

Reduce your health risks now. Learn more about personalized physician supervised preventative programs and the science behind functional medicine.

Americans catch an estimated 1 billion colds each year

And by this time of year, as weary cold sufferers line up at local pharmacies, it may not sound surprising that Americans spend at least $4.2 billion annually on over-the-counter cough and cold medications — and even more on alternative therapies.

Yet here’s the dirty little secret about the common cold:

Nothing cures it. Nothing makes it go away faster.

And there’s little evidence that popular treatments really do much to relieve symptoms.

“In a nutshell, there’s nothing that works,” says Aaron Glatt, a doctor and spokesman for the Infectious Disease Society of America. “There’s a tremendous industry out there, and some people really swear by them. But there really aren’t great studies to show any benefit.”

Research has found that some therapies — from echinacea to humidifiers, vitamin C, zinc, vapor rubs and Neti pots — have little to no measurable benefit, say pediatricians Rachel Vreeman and Aaron Carroll, authors of Don’t Swallow Your Gum! Myths, Half-Truths and Outright Lies About Your Body and Health.

For other folksy favorites — such as chicken soup, garlic, honey or hot tea — there’s just not enough data to tell, Vreeman and Carroll says. That’s partly because big drug companies don’t tend to spent much money to research products, such as honey and tea, that people can buy anywhere.

“When it comes to over-the-counter therapies, they’re pretty cheap, so people will buy them anyway,” Carroll says. “But if they don’t work, you shouldn’t be surprised.. .. But it’s all about symptom relief. So if tea makes you feel better, go ahead. If a warm blanket and a pillow makes you feel better, do it.”

In some cases, however, even over-the counter drugs can have serious side effects. The Food and Drug Administration has warned not to use zinc nasal products — touted to prevent and treat colds — because of concerns that it can make people lose their sense of smell.

In children, cough and cold remedies are not only ineffective, but can be harmful, Vreeman and Carroll says. That’s why manufacturers no longer sell these drugs for kids under 4.

Since colds go away on their own after about a week, improving a little each day after symptoms peak, it’s easy for people to believe that their medicines — rather than time — should get the credit, says James Taylor, a pediatrics professor at the University of Washington. And cold sufferers are so desperate for help, studies show, that even placebos can make people feel better about one-third of the time.

USA TODAY asked experts to summarize the evidence for some of the most commonly used remedies.

•Decongestants

In the lab, these over-the-counter drugs look like a winner.

Decongestants shrink dilated blood vessels in the nose, which should provide relief for that stuffed-up feeling, says Elizabeth Funderbunk, a spokeswoman for the Consumer Healthcare Products Association.
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In the real world, however, their effects are modest at best.

A single dose of a nasal decongestant reduces adults’ symptoms by 6% according to a 2007 Cochrane Systematic Review. Additional doses reduced symptoms by 4%.

To reduce the risk of side effects, it’s best to take the lowest dose possible — such as found in nasal sprays, says Sidney Wolfe, director of Public Citizen’s Health Research Group.Even then, people shouldn’t use nasal sprays for more than a few days, because overuse can actually increase congestion. Wolfe also advises avoiding products that treat multiple symptoms, because they typically provide way more medication than people really need.

•Vitamin C

Nobel Prize winner Linus Pauling popularized the idea of taking vitamin C to prevent colds.

But a review of studies with a total of 11,000 people found that taking 200 milligrams or more of vitamin C a day didn’t reduce the chance of getting a cold, and it reduced the duration of a cold only by a matter of hours. The only people who got any protection against colds were those whose bodies were under extreme stress, such as soldiers in sub-arctic conditions, according to the National Center for Complementary and Alternative Medicine (NCCAM), part of the National Institutes of Health.

•Echinacea

Scientists have been intrigued by echinacea because of laboratory studies suggesting that some constituents of this herbal folk remedy decrease inflammation, while others appear to boost the immune system.

But improving immunity in a human being is far more complicated than in a petri dish, says Wendy Weber, a program officer at NCCAM. She notes that there are three species of echinacea that are used medicinally, and concentrations can vary from bottle to bottle.

Three studies found by NCCAM concluded that echinacea was no better than a placebo for treating or preventing a cold. While doctors continue to research echinacea, Weber says there isn’t yet enough research to prescribe it. And although echninacea is the most commonly used herbal supplement in children, studies also show it can slightly increase kids’ risk of rash.

•Zinc

While a 2007 research review found that zinc nasal gel helped improve cold symptoms, the Food and Drug Administration now warns people to avoid them, because of concerns that the products can make people lose their sense of smell.

In a 2007 review of the research, only one of four high-quality studies found that a zinc product — a nasal gel — helped to improve cold symptoms. But before you stock up, consider this: The Food and Drug Administration in 2009 warned consumers not to use any intranasal zinc products because of concerns that it can make people lose their sense of smell. While zinc lozenges may not cause any lasting damage, they taste so awful that they can cause nausea, say Carroll and Vreeman. Also, the 2007 review found that they didn’t work.

•Honey

Generations have turned to hot tea with honey to soothe a sore throat.

One study, in which children over age 2 were given up to 2 teaspoons of honey before bedtime, found that honey did help reduce coughing. But Weber notes that researchers need to confirm these findings with additional studies. She says honey should never be given to children under age 1 because of the risk of botulism. And while many people like honey cough drops, Weber notes that they can a choking hazard to babies and toddlers.

•Eucalyptus oil and vapor rubs

In a recent study in Pediatrics, children with cough and cold symptoms improved the most when their parents rubbed their chests with Vicks VapoRub, a strongly scented gel made with camphor, menthol and eucalyptus oil, compared with those given a placebo.

But it’s hard to know if Vicks really deserves the credit, says Daniel Frattarelli, a doctor and spokesman for the American Academy of Pediatrics. Because VapoRub smells so strong, parents could tell if they were using the real thing or a placebo, even though researchers did their best to “blind” parents to which treatment they were using. Still, there were no serious side effects, so Frattarelli says the study, funded by manufacturer Procter and Gamble, suggests that VapoRub seems safe.

•Nasal saline (such as Neti pots), humidifiers, hot steam

Even many doctors tell patients to treat congestion with devices such as Neti pots, which flush out the nose with warm, salty water; with humidifiers or by taking steamy showers.

While these treatments seem safe and helpful, there’s also no data that they work, Glatt says.

When using a humidifier, Santa suggests using cool mist, rather than hot steam, which can scald small children.

“I’m not aware of any studies showing a humidifier can help (children) to sleep” when congested, Glatt says. “But I’m never going to argue with a parent who tells me that it does.”

Starting the year on the right foot

For centuries, Chinese have looked to feng shui to help keep their lives balanced. Feng shui aims to improve and harness the flow of positive Chi (energy) and harness it favorably. Feng shui has also been assimilated into Filipino culture as a venue for healthy living.

As we usher in the year of the Golden (Metal) Rabbit today. Feng shui experts give their forecasts for the coming year. Read below, find and discern the path you wish to take to make this New Year a lucky one.

For people born in the year of the Ox, Dragon, Tiger, and Snake it will be a good one. They will enjoy good fortune as opportunities come their way. They should keep their mind focused and if they do, they are most likely to reach their goals.

Individuals born under the year of the Tiger, Rabbit, Snake and Horse are advised to take precaution with regard to health concerns as stress as sickness may hinder their progress this year. Charms and crystals promote and improve physical, mental and spiritual health. Brass Wu Lou with eight immortals and the jade bracelet are said to counteract bad health.

Medical practitioners firmly believe that practicing any form of alternative medicine should be accompanied by expert advice. And there is nothing wrong with applying feng shui principles to enhance wellness.

Healthway Medical believes that it is important to put a high premium on one’s.

“Healthway has been consistently campaigning toward an active and healthy lifestyle, “says Carmie De Leon, vice president for sales and marketing.

The clinic offers HealthCheQ Gold, an executive checkup in partnership with Nurture Spa. Its packages include complete laboratory and imaging studies, a comprehensive physical evaluation, and special examinations combined with an anti-stress activity in a spa. It is a medical checkup that people look forward to.

The packages offer personalized convenience, quality hygienic medical procedures, online appointment or scheduling, results within 72 hours, quality hard-copy report for future reference, pampering experience from Healthway’s sister company (Clarity Aesthetic Medical and Dental Center), chauffeured service from Healthway Clinic to Nurture Spa Village in Tagaytay, and a choice of overnight wellness experience.

It also offers medical cards that can now be even personalized; Healthway card, Alagang Healthway, Junior Privilege and Platinum card. They all contain a medical package that fits the budget. “And as an advocate of this campaign, we encourage everyone to have their health check and to eat and live healthy. Let’s all start the year right by being healthy and welcome the Chinese New Year with a smile,” De Leon said.

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Natural Remedies Today

2011-02-03 / Wellness / No Comment

Home remedies that work

In this complicated world we live in, here are a few amazingly simple home remedies that really work. A friend sent them to me and vouched they’re for real, so I’m sharing them this week with all our readers. Enjoy.

Amazingly Simple Home Remedies

Avoid cutting yourself when slicing vegetables by getting someone else to hold the vegetables while you chop.

For high blood pressure sufferers, simply cut yourself and bleed for a few minutes, thus reducing the pressure on your veins. Remember to use a timer.

A mousetrap placed on top of your alarm clock will prevent you from rolling over and going back to sleep after you the snooze button.

If you have a bad cough, take a large dose of laxatives. Then you’ll be afraid to cough.

You only need two tools in life – WD-40 and duct tape. If it doesn’t move and should, use the WD-40. If it shouldn’t move and does, use the duct tape.

If you can’t fix it with a hammer, you’ve got an electrical problem.

Donating organs

I recently renewed my driver’s license and discovered now you can do everything by mail including even donating your organs by simply checking a donor’s box.

Did you know…

19 people die everyday waiting for an organ transplant in the U.S

Millions of people in the U.S. need an organ transplant, but only 100,000 are registered on the government’s current deceased organ donor list because there are too few deceased donor organs.

MatchingDonors.com has become the world’s largest and most successful nonprofit organization promoting and registering living organ donation.

Currently, patients waiting for an organ donation are placed on a national waiting list through the United Network for Organ Sharing.

A computer system matches patients to donor organs according to objective criteria such as blood and tissue type, immune status, medical urgency and time spent on the waiting list – the average time to receive a deceased organ is seven to nine years on this list.

This ranking system determines which patients are offered available organs. This process is extremely important in anyone’s organ search, but now MatchingDonors.com offers a way to enhance the search with a more active approach – the average time a person receives an organ from MatchingDonors.com is less than six months.

In collaboration with a number of health officials, MatchingDonors.com (a 501c3 nonprofit organization) has launched a public education campaign throughout the United States to help people recognize that they can be a living organ donor and to encourage them to register as a living organ donor.

Kitchen Cures:Taking advantage of natural remedies

Piercing wind chills and teeth-chattering temperatures aside, the unavoidable spread of disease is the bane of every student’s existence during these long winter months.

Only when an illness strikes hard enough to challenge our pain/discomfort tolerances do we consider medical attention, but antibiotics, experts say, are not the answer for all problems.

The Mayo Clinic advises a doctor’s visit for bacterial infections such as strep throat and UTIs, but explains that viral infections, such as the common cold, influenza and some ear infections just take rest and time for the body to heal.

Home remedies may be the best solution for those who don’t want to risk antibiotic resistance or who are without health insurance, and they are easy and cheap enough for anyone to try.

Below are a collection of popular suggestions for natural medicines meant to relieve aches and pains during the recovery process.
Ear infection

It’s best to visit a doctor for an earache in order to find out if it’s a bacterial/fungal infection such as swimmer’s ear or a viral infection, which are often a result of a cold.

• Steam: Microwave a wet cloth in a mug until it steams, then place over ear for a few minutes and afterwards, let the ear drain.

• Onions: Bake an onion in oven at 350 for an hour or microwave until it can be pricked easily with a fork. Then place onion in a mug and slice it open so it steams. Place your ear over the mug until no more steam is being produced. This should relieve pain immediately and prevent further infection.

• Lemons: Squeeze some lemon juice in your ear, then let it drain after a few seconds. The lemon’s acidity neutralizes the base properties of the bacteria, making it a very harsh environment for their survival.
Coughs/sore throat

• Ginger: It’s easy to prepare this as a tea. To do this, cut pieces of raw ginger into small pieces and dump into boiling water before adding tea leaves.

• Okra: Boil down sliced up pieces of okra, also known as lady’s fingers, into a pot and inhale the steam once or twice a day to help with throat irritation. Okra can be found at most Columbus grocery stores for $2.99 per pound.
Allergies or sinus infections

• Neti Pot: To relieve nasal congestion, a neti pot, which resembles an Aladdinesque teapot-lamp, is used to pour a saline solution up the nose. Just mix one cup warm water for every ¼ teaspoon non-iodized salt. This stream of water then flows out the other nostril, resulting in a clean, pain-free nasal passage.

• To illustrate how effectively this technique works, take into account the thousands of years Indian yogis have been using this practice to cleanse their naval cavities. Neti pots can be found locally at Walgreens for $7 and CVS for $13 but a wider selection and price range is available online as well.
Indigestion

• Fennel or caraway seeds: The best way these seeds work is to put about a teaspoon of them in a cup and pour in boiling water. Cover the cup, wait 10 minutes, then thoroughly strain out the seeds before drinking this concoction. Drink about three cups a day on an empty stomach for best results.

• Cinnamon: Stir in ¼ to ½ teaspoon of cinnamon powder into a cup of hot cocoa or hot water for tea. The properties of this Southeast Asian spice help your digestive tract function smoothly. The water will also help with this. In fact, 6 to 8 glasses daily is the recommended amount to maintain healthy intestines.

• Herbal tea: Even something as simple as drinking ginger, thyme or mint tea on an empty stomach can help calm the stomach.

• Baking soda: This recipe can be used for all flu-like symptoms. To make your own Alka-Seltzer, mix ½ teaspoon of baking soda in a ½ cup of water. For a citrus flavor, just add ½ teaspoon of lemon juice. This advice is not recommended for people watching sodium intake or those with high blood pressure.
Warts

• Duct tape: Place a small rectangle of duct tape over the wart and change every three hours. To avoid curious inquiries, you can keep a band aid over the area. One study found this treatment more effective than the liquid-nitrogen freezing process most doctors use (http://archpedi.ama-assn.org).

• Pineapple: Apply fresh pineapple to the wart for several times a day. This should remove the wart in about two to three days.

• Camphor oil: Coat the area with camphor oil every few days and the wart should disappear within a week.

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Acupuncture

Arizona acupuncture school offered free stress treatment

TUCSON, Ariz. — The Arizona School of Acupuncture and Oriental Medicine offered some mental relief from the Tucson shootings. It hosted free walk-in trauma and stress recovery treatments Monday.

Volunteers performed 45-minute community style acupuncture treatments by inserting five one time use needles in each person’s outer ear.

“Often the nervous systems gets stuck in a state of fight or flight and its difficult for them to sleep or think. The acupuncture treatment is like pressing the reset button for the nervous system that allows them to calm down and de-stress,” said Melanie Rubin from Acupuncturists Without Borders.

People who are treated typically feel a tiny pinch when the needles go in. That quickly gives way to a feeling of deep relaxation.

New Acupuncture and Asian Medicine Clinic Opens in Studio City

Bokchi Acupuncture Clinic is proud to announce the opening of its office in Studio City, California, serving the entire San Fernando Valley and beyond. The clinic specializes in Bokchi medicine and acupuncture and treats an array of common ailments such as respiratory problems, musculoskeletal disorders, allergies, headaches, depression and anxiety.

Bokchi Acupuncture Clinic’s therapies focus on balancing energy and eliminating the body’s toxic elements. Acupuncture uses thin sterilized needles to improve energy flow, reducing pain and restoring vitality, health and function to organs, joints and tissues. “Bokchi Medicine” utilizes the art of abdominal palpation by the hand of a trained professional. Areas of pain and sensitivity are identified. These areas are toxic elements accumulated in the body. A clinician then blends Asian herbs into teas, pills and powders to formulate a detox program suited for each patient’s medical needs.

The clinic offers other treatments as well. Trigger point therapy, developed by Dr. Janet Travell, identifies and resolves painful trigger points which are found in skeletal muscle fibers. SI Technique, developed by Sung-Im Park, uses two probes which have bipolar magnetic energy to correct body energy flow. Clinicians can also monitor their patients’ progress using the Hematology Analyzer, which measures the ratio between granulocyte and lymphocyte activity.

All three of the clinic’s members are licensed acupuncturists with experience in Asian medicine. Their methods are based on the Korean modality, as taught by the Korean Bokchi Medicine Association.

“We are proud that we are the first clinic in the USA to introduce this Korean modality,” said co-founder Edward Jwa.

Bokchi Acupuncture Clinic’s website outlines its many services, and features a section where patients can ask questions and leave comments.

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Anxiety Treatment Today

2011-01-29 / Mental Health / No Comment

Alleged Ponzi schemer to get drug treatment in jail

TEXAS, United States, Thursday January 27, 2011 – Fraud accused Allen Stanford will have to remain in jail to get the treatment he needs for an addiction to anti-anxiety medication, a judge ruled yesterday as he put in writing an earlier ruling that the former billionaire is unfit to stand trial.

US District David Hittner said that the alleged Ponzi schemer would not be allowed to go to a private facility as his lawyers had requested. He said Stanford would get what he needed at a prison hospital and would also receive further psychiatric testing to determine his competence to stand trial later on.

“The court’s finding that Stanford is incompetent…does not alter the court’s finding that Stanford is a flight risk and that no combination of conditions of pretrial release can reasonably assure his appearance at trial,” Hittner wrote.

Stanford’s trial stems from allegations that he defrauded investors of US$7 billion through the sale of certificates of deposit at the Stanford International Bank in Antigua. Prosecutors say he conducted a Ponzi scheme in which earlier investors are paid not from returns on their investments, but with the money paid in by later investors.

He was to face 21 charges in a trial that was scheduled to start Monday. But after Hittner heard from one government and two defence psychiatrists earlier this month that Stanford had been taking high doses of anti-anxiety and antidepressant drugs that left him unable to assist in preparing his own defence, the judge postponed the trial indefinitely and said he would set a new date only after Stanford’s had detoxified and was declared competent.

In his written ruling, Judge Hittner said while the three psychiatrists could not identify the exact cause of Stanford’s diminished mental capacity, they all agreed it could be one or a combination of over-medication, which has led to an addiction; brain damage caused by the head injury he sustained in September 2009 in a prison fight; and/or Major Depressive Disorder, also known as clinical depression.

All the psychiatrists agreed that Stanford should be withdrawn from his medications, a process that could take up to six months.

Judge Hittner has advised both the defence and prosecutors to diligently prepare their cases in the meantime.

When Worries Never End: Generalized Anxiety Disorder

Some people are worriers, or are just a little more anxious than others. But when that anxiety starts to take over your life, when you find you can’t make it through the day without getting worked up about something, it’s more than just anxiety. It might be generalized anxiety disorder.

Generalized Anxiety Disorder: Endless Worry

Unlike phobias or other more specific anxiety disorders, generalized anxiety disorder, or GAD, isn’t a fear or worry about one particular thing or things. Instead, it’s constant worry — not about major events, but about the little things that you do every day. This level of anxiety is usually considered a disorder when it continues for more than six months and starts to affect daily life. People with generalized anxiety disorder excessively worry about things like their job, their money situation, their health problems, and their loved ones.

“People who have generalized anxiety feel it in multiple situations. They describe feeling tensions that they cannot first label as tension-producing, that they feel are innocuous situations, and in effect they live a life in which they have a sense of foreboding about everything,” says Charles Goodstein, MD, a clinical professor of psychiatry at New York University Langone Medical Center. “They cannot localize it.”

Other symptoms of generalized anxiety disorder include:
Always feeling edgy or tense
Constant anxiety and worrying
Anxiety that is excessive given the circumstances (irrational anxiety)
Having a hard time concentrating
Feeling shaky, tired, and cranky
Frequent headaches
Insomnia and other sleep problems
Physical symptoms like upset stomach or diarrhea, difficulty catching your breath, rapid heart rate, and sweating

Almost seven million adults in the United States deal with generalized anxiety disorder, a little over 3 percent of the total population. While anyone can get the disorder, twice as many women as men have it. And generalized anxiety disorder can strike as early as childhood, although symptoms may not show up until middle age or later.

Hypericum perforatum treatment: effect on behaviour and neurogenesis in a chronic stress model in mice

Extracts of Hypericum perforatum (St. John’s wort) have been traditionally recommended for a wide range of medical conditions, in particular mild-to-moderate depression.

The present study was designed to investigate the effect of Hypericum perforatum treatment in a mouse model of anxiety/depressive-like behavior, induced by chronic corticosterone administration.

Methods: CD1 mice were submitted to 7 weeks corticosterone administration and then behavioral tests as Open Field (OF), Novelty-Suppressed Feeding (NSF), Forced Swim Test (FST) were performed. Cell proliferation in hippocampal dentate gyrus (DG) was investigated by both5-bromo-2′-deoxyuridine (BrdU) and doublecortin (DCX) immunohistochemistry techniques and stereological procedure was used to quantify labeled cells.

Golgi-impregnation method was used to evaluate changes in dendritic spines in DG. Hypericum perforatum (30mg/Kg) has been administered for 3 weeks and then neural development in the adult hippocampus and behavioral changes have been examined.

Results: The anxiety/depressive-like state due to chronic corticosterone treatment was reversed by exogenous administration of Hypericum perforatum; the proliferation of progenitor cells in mice hippocampus was significantly reduced under chronic corticosterone treatment, whereas a long term treatment with Hypericum perforatum prevented the corticosterone-induced decrease in hippocampal cell proliferation.

Corticosterone-treated mice exhibited a reduced spine density that was ameliorated by Hypericum perforatum administration.

Conclusion: These results provide evidence of morphological adaptations occurring in mature hippocampal neurons that might underlie resilient responses to chronic stress and contribute to the therapeutic effects of chronic Hypericum perforatum treatment.

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Nutrition News

2011-01-28 / Nutrition & Diets / No Comment

Mead Johnson 4Q profit jumps 56 percent

GLENVIEW, Ill. (AP) — Infant formula maker Mead Johnson Nutrition Co. said Thursday its profit climbed 56 percent in the fourth quarter as sales in Asia and Latin America continued to improve. But its forecast for 2011 was short of Wall Street estimates.

The maker of Enfamil said its net income increased to $99.6 million, or 48 cents per share, in the last three months of 2010 from $64 million, or 31 cents per share, a year earlier.

Excluding one-time costs related to its initial public offering, severance expenses, legal costs, and other items, the company said it earned 57 cents per share.

Its revenue rose 13 percent to $803.7 million from $714.4 million.

Analysts expected earnings of 56 cents per share on revenue of $806.3 million, according to estimates compiled by FactSet.

Mead Johnson said revenue in Latin America and Asia rose a combined 20 percent to $509.7 million. It said business was especially strong throughout Latin America and in China and Hong Kong. Sales in North America and Europe rose 2 percent to $294 million. It added that changes in foreign currency exchange rates boosted its sales by about 2 percent.

Mead Johnson was a wholly owned unit of drugmaker Bristol-Myers Squibb Co. until it completed its IPO in February 2009. The company was fully separated from Bristol-Myers in December 2009.

Its annual profit grew 13 percent to $452.7 million, or $2.20 per share, from $399.6 million, or $1.99 per share, in 2009. Revenue increased 11 percent to $3.14 billion from $2.83 billion.

Mead Johnson said it expects an adjusted profit of $2.55 to $2.65 per share in 2011. Net sales are expected to grow 7 to 8 percent, which suggests a total of $3.36 billion to $3.39 billion. On average, analysts are forecasting a profit of $2.73 per share and $3.44 billion in revenue.

Shares of Mead Johnson Nutrition fell 28 cents to $59.74 in afternoon trading.

‘Nutrition Keys’ Coming to the Front of Food Packages

MORGANTOWN — The Grocery Manufacturers Association along with the Food Marketing Institute has started putting some labels on the front of their products called “Nutrition Keys”.
“With it being on the front of the package it’s hoped that its going to be noticeable and more informative to consumers.”

Certified dietician Cindy Fitch with the West Virginia University Extension Service says the more visible the information the better.

The labels list calories, saturated fat, sugar, sodium and other nutrients.

“The more that we draw attention to the food that we eat and what’s in the food that we eat the better off we are,” says Fitch.

“I don’t think that people realize how much fat or sodium is in the foods that they buy,” she said.

Some critics say the nutrition keys are a way to get out of using labels that are already being developed by the Food and Drug Administration.

Fitch says she noticed the keys are lacking a very important feature; the serving size.

“We have a big misconception about serving sizes in this country. We tend to eat a pretty large serving sizes and not pay attention to what the nutrition facts label says the serving size is and that’s not on the front of the package and I think it should be,” says Fitch.

The government had the Institute of Medicine conduct a study about the labels to be reviewed by the FDA.

Michelle Obama in SC, sees Army fitness, food

FORT JACKSON, S.C. (AP) — First lady Michelle Obama is visiting the Army’s largest training post to see how the military turns couch potato recruits into strong and nutrition-minded soldiers.

The first lady arrived Thursday to address the latest crop of new soldiers at their graduation ceremony at Fort Jackson in central South Carolina. She also was to hear about Army efforts to turn unfit teens into warriors.

Obama’s focus on making children healthier intersects with the nation’s need to field tough troops for the Army.

Fort Jackson trains more than 60,000 soldiers annually, including more than half of the Army’s female soldiers.

Lt. Gen. Mark Hertling is briefing the first lady on how new soldiers are given exercises for core body strength and stamina. Mess halls now feature more dark greens, whole grains and fat-free milk.

THIS IS A BREAKING NEWS UPDATE. Check back soon for further information. AP’s earlier story is below.

FORT JACKSON, S.C. (AP) — First lady Michelle Obama is visiting the Army’s largest training post to see how the military turns couch potato recruits into strong and nutrition-minded soldiers.

The first lady, who has taken on the cause of battling childhood obesity, was to speak Thursday to the latest crop of new soldiers at their graduation ceremony at Fort Jackson in central South Carolina.

Her battle against children’s lack of fitness intersects with the nation’s need to field fit troops for the Army.

Fort Jackson, which trains more than 60,000 soldiers annually and more than half the Army’s female soldiers, is one of the service’s five major posts for basic and advanced individual training.

Lt. Gen. Mark Hertling, who recently overhauled the way the Army feeds its troops during training, also revamped the Army’s physical training regimen.

Hertling was slated to brief the first lady on how new soldiers are given exercises for core body strength and stamina. Bayonet drills have been dropped in favor of zigzag sprints, pugil stick workouts and stepped up calisthenics to increase power, strength and agility for soldiers facing rigorous campaigns in places like Afghanistan.

Mess halls now feature dark greens, whole grains and no-fat milk instead of calorie-laden fried foods, sugary desserts and sodas.

Red, yellow and green markings above each food item tell soldiers which foods are good for their energy level, which ones will keep them full, and which should be eaten in moderation.

Drill sergeants now call out recruits who don’t put enough fruits and veggies on their plates, and hold hour-long sessions on performance nutrition to help them understand the Army wants “soldier athletes.”

Army officials worry the nation’s security is at risk because fewer than one in four 17 to 24 year-olds are fully qualified to enter the military because of health, weight, or legal reasons.

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Obesity Treatment News

Obesity puts children and adults at risk

According to a new study at the Pediatrics Department of the University of Chicago, children who sleep for at least nine hours do not have problems of obesity and the accompanying metabolic disorders like diabetes and cardiovascular disease.
The study indicated that children who consistently get nine to 10 hours of sleep on both weekdays and weekends have the healthiest metabolic profile. “Good sleep routines and sleeping the right amount is the best healthy proposition,” lead author David Gozal said.
Parents should watch for symptoms that indicate their children need to sleep more. Being cranky or less alert are just two of these. Consequences seen during school would probably be behavior problems, poorer execution of cognitive tests and physical injuries.
Catching up on sleep over the weekend is believed to help to a certain extent but those children who were obese already had shorter and more irregular patterns of sleep. These are also the ones who had higher insulin levels — which can lead to type 2 diabetes over a prolonged period — higher levels of “bad” (LDL) cholesterol and higher levels of C-reactive protein, which has been linked to heart disease in later life.
Obesity is defined as an excessively high amount of body fat (or adipose tissue) in relation to lean body mass. The amount of body fat includes concern for both the distribution of fat throughout the body and the size of adipose tissue deposits. Weight standards can be measured in many different ways. The most common is body mass index.
BMI represents weight levels associated with the lowest overall risk to health. BMI is a mathematical formula in which a person’s body weight in kilograms is divided by the square of his or her height in meters. BMI is more highly correlated with body fat than any other indicator of height and weight. Desirable BMI levels may vary with age. According to the National Institutes of Health clinical guidelines on the identification, evaluation and treatment of overweight and obese adults, all adults (aged 18 years or older) who have a BMI of 25 or more are considered at risk for premature death and disability. Individuals with a BMI of 30 or more are considered obese. Health risks increase as severity of the person’s obesity increases.
Other weight tables have been created by the Metropolitan Life Insurance Company. Theirs is based on their client population.
Factors that contribute to child, adolescent and adult obesity include:
Modifiable (things that can be changed) causes such as:
• Physical activity: lack of regular exercise
• Sedentary behavior: high frequency of television viewing, computer usage and similar behavior that takes up time that could be used for physical activity
• Socioeconomic status: low family incomes and non-working parents
• Eating habits: over-consumption of high-calorie foods and eating patterns such as eating when not hungry, eating while watching TV or doing homework
• Environment: factors include over-exposure to advertising of foods that promote high-calorie foods and lack of recreational facilities
Non-changeable causes include:
• Genetics: children of obese and overweight parents are at greater risk of obesity
Obese people are at risk of developing one or more serious medical conditions, which can cause poor health and premature death. Obesity is associated with more than 30 medical conditions and scientific evidence has established strong relationships with increases in deaths from all causes due to obesity. Preliminary data also shows the impact of obesity on various other conditions. Weight loss of about 10 percent of body weight, for people who are overweight or obese, can improve some obesity-related medical conditions including diabetes and hypertension.
Just a few facts on obesity-related medical conditions:
• More than 75 percent of hypertension cases are reported to be directly linked to obesity.
• Obesity contributes to the main cause of gout — the deposit of uric acid crystals in joints and tissue.
• As many as 90 percent of individuals with type 2 diabetes are reported to be overweight or obese. Obesity has been found to be the largest environmental factor on the prevalence of diabetes in a population.
• Postmenopausal women with obesity have a higher risk of developing breast cancer. In addition, weight gain after menopause may also increase breast cancer risk. Women who gain nearly 45 pounds or more after age 18 are twice as likely to develop breast cancer after menopause than those who remain at a stable weight.
• Women with obesity have three to four times the risk of endometrial cancer than women with lower BMI.
• The effects of obesity on cardiovascular health can begin in childhood, which increases the risk of developing cardiovascular disease as an adult.
• Obesity has been found to decrease the body’s resistance to harmful organisms. A decrease in the activity of scavenger cells, which destroy bacteria and foreign organisms in the body, has been observed in patients with obesity.
If losing weight is high on your list of New Year’s resolutions for your child or yourself, check out “The Top 10 Habits That Can Help You Lose Weight” by Kathleen M. Zelman on WEBMD.

Obesity, Legacy of Smoking Leave Americans Behind in Life Expectancy

America lags many other nations in life expectancy, largely because of obesity and, in years past, lots of smoking. That, at least, is the conclusion of a new study from the National Research Council, the main operating arm of the National Academy of Sciences and the National Academy of Engineering.

The report mainly blames the nation’s once-prevalent smoking habit. While only 20 percent of the adult population smokes today, the figure was 40 percent in 1960, and many 1960 smokers are still suffering the effects.

“Fifty years ago, smoking was much more widespread in the United States than in Europe or Japan: a greater proportion of Americans smoked and smoked more intensively than was the case in other countries,” the authors wrote, as Reuters reports.

“Other factors, such as obesity, diet, exercise, and economic inequality, also have likely played a role in the current gap and divergence between the United States and other countries,” the study said.

At 78.3 years, U.S. life expectancy at birth ranks 36th in the world, behind most of Europe, parts of Asia and even Cuba, according to the United Nations. Japan’s life expectancy of 83 years is the world’s highest.

The report had some good news for Americans, however. The authors said that the nation’s declining smoking numbers will result in higher life expectancies in the coming decades.

Turn down the thermostat, your heater may be making you fat

Linda Carroll writes: Lowering your thermostat may reduce not only your spending, but also your weight, a new study suggests.

Researchers suspect that rising indoor temperatures in British and American homes may have contributed to the obesity epidemic. The theory is that we burn fewer calories when our bodies don’t have to work as hard to stay warm, according to a report published in Obesity Reviews.
“Research into the environmental drivers behind obesity, rather than the genetic ones, has tended to focus on diet and exercise – which are undoubtedly the major contributors,” said the study’s lead author, Dr. Fiona Johnson, of the UK Health Behavior Research Centre at University College, London. “However, it is possible that other environmental factors, such as winter indoor temperatures, may also have a contributing role.”

Johnson and her colleagues scrutinized data on indoor temperatures in both the United Kingdom and the United States. They found that both British and American households have bumped up their thermostats several degrees over the last few decades.

For example, bedrooms in the U.S. were heated to an average of 66.7 degrees in the late 1980s, versus 68.4 degrees in 2005. The differences were more striking in British bedrooms, where the average temperature climbed from 59.4 degrees in 1978 to 65.3 degrees in 1996.

Studies have shown that slightly chillier temperatures can lead to increased energy expenditures, Johnson noted. And that’s true even when people bundle up.

“Increased time spent indoors, widespread access to central heating and air conditioning, and increased expectations of thermal comfort all contribute to restricting the range of temperatures we experience in daily life and reduce the time our bodies spend under mild thermal stress – meaning we’re burning less energy,” Johnson said.

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Gout Treatment News

2011-01-26 / Pain Management / No Comment

Dealing with gout — the malady of kings

OAK RIDGE, Tenn. —

Gout is the most common type of inflammatory arthritis in the United States and the number of cases has doubled in the last two decades. An attack usually involves a single joint in the legs or feet, particularly the big toe, and may cause severe pain for up to a week.

At the heart of gout is a class of molecules called “purines.” Most purines are part of the structure of DNA and because DNA is found in cells, cellular foods like meat have a lot of purines. When purines are broken down into uric acid, it may accumulate in a joint and create symptoms of pain, redness, and swelling.

Impaired uric acid excretion by our kidneys is worsened by many prescription and some over-the-counter drugs. Diuretics and low-dose aspirin are the big offenders. High-fructose sweeteners and alcohol are food sources that also impair uric acid excretion.

Diabetes and a pre-diabetic condition called “metabolic syndrome” are now epidemic in the United States. These conditions contribute to gout by both altering uric acid metabolism and by creating renal insufficiency. Sixty percent of gout sufferers now have metabolic syndrome.

There is often no relationship between blood levels of uric acid and the timing of an acute attack of gout. For diagnosis, the best strategy is to have your doctor perform testing two weeks after the attack.

At that time, if your blood level of uric acid is elevated, you likely have gout. The diagnosis is unlikely if the level is less than 4 mgj dl. In the event of a positive diagnosis, you probably have a problem excreting uric acid instead of overproducing it if your 24-hour urine uric acid is less than 800 mg.

Treatment of an acute gout attack is often best handled with early use of a non-steroidal, anti-inflammatory drug like indomethacin. Colchicine is a drug that has been used for gout in one form or another for centuries but has only recently been approved by the FDA for this purpose. Two pills at onset of symptoms and one more in two hours is all that should be used. Higher doses do not work better and may have toxic effects. Oral or intramuscular steroids may also be helpful.

A drug called probenecid helps promote excretion of uric acid. It may be useful if someone cannot take indomethacin or colchine.

For those that have had three or more gout attacks in a given year, a preventive medicine that limits uric acid production may be helpful. Allopurinol has been widely used for this purpose. Another drug in the same category is now available. There is no good evidence that it works better and it is considerably more expensive. A new drug is in the pipeline that uses a slightly different mechanism to decrease uric acid production. Expect it to be expensive also.

Always discuss strategy with your doctor before considering medicine use, but remember, as with most maladies, the best management of gout is still prevention.

A study of 89,000 older female nurses shows that drinking one to three cups of coffee daily can reduce the risk of developing gout by 22 percent. Four cups or more can reduce the risk by 57 percent. Decaf does not carry the same risk reduction and other caffeinated drinks do not work.

Vitamin C can promote uric acid excretion by limiting its re-absorption in the kidneys. A 20-year study of 47,000 men showed that daily intake of at least 250 mg of Vitamin C was associated with fewer attacks of gout. There was a 17 percent decrease in risk for each 500 mg increase in Vitamin C consumed.

Losing weight and increasing exercise can decrease the risk of gout from diabetes and metabolic syndrome. Limiting alcohol and refined high-fructose foods like soft drinks will also significantly decrease the risk. Decreasing meat consumption, particularly organ and game meats, as well as seafood can decrease the likelihood of gout. Increasing low-fat dairy can also decrease the risk.

Moderate intake of purine-rich vegetables like spinach, beans, peas, mushrooms, oatmeal, and wheat bran have not been found to significantly increase the risk of gout.

Trauma can precipitate an attack of gout, so always protect your feet and knees.

Gout may have once been the malady of kings, but now we have another reason to live longer and healthier lives than Henry the VIII. We know what causes gout and we know how to treat it and prevent it.

Ardea Follows Positive Gout Results with $71.5M Offering

January already had been a pretty good month for Ardea Biosciences Inc. and it got even better on Thursday.

San Diego-based Ardea followed up its announcement earlier this month of positive, preliminary, top-line results from its Phase IIb study of RDEA594 in combination with the current standard of care for the treatment of gout, allopurinol, with an underwritten public offering of 2.75 million shares of common stock priced at $26 a share, about 3 percent below Wednesday’s closing price. The company expects gross proceeds of about $71.5 million.

Ardea stock (NASDAQ:RDEA) was down 56 cents, to close at $26.25 Thursday.

Ardea also earned a $15 million milestone payment earlier this month from partner Bayer HealthCare AG under a 2009 license agreement concerning MEK inhibitor compounds. Bayer’s initiation of a Phase II trial of BAY 86-9766 with sorafenib in hepatocellular carcinoma triggered the payment. The payment brought Ardea’s total under the agreement to $50 million to date, and the company could receive as much as $357 million more in future milestones. (See BioWorld Today, April 29, 2009.)

BofA Merrill Lynch and Jefferies & Co. Inc. are joint book-running managers with JMP Securities, Brean Murray, Carret & Co. and Roth Capital Partners acting as co-managers. The underwriters have a 30-day option to purchase an additional 412,500 shares to cover overallotments, which potentially could raise an additional $10.7 million. The offering is expected to close Jan. 25.

The company said it anticipates using the proceeds for clinical trial expenses – including RDEA594, which is expected to enter Phase III testing this year – research and development expenses and working capital.

John Beck, Ardea’s CFO and senior vice president finance/operations, told BioWorld Today that he expects some of the funds to go toward the Phase III program for RDEA594, but said that it is too soon to pin down specifics.

“Because we have not yet had our end of Phase II meetings with U.S. and EU regulatory authorities, we are unable at this time to provide specifics regarding the scope of our Phase III program for RDEA594,” Beck said. “However, we do believe that the proceeds from this raise, together with our existing resources, provide a strong financial foundation as we plan for Phase III.”

Beck said that the company’s preliminary, unaudited cash balance at the end of 2010 was approximately $80 million. Proceeds from the new financing, net of expenses and conservatively assuming the underwriter’s allotment is not exercised, plus the $15 million milestone payment from Bayer brings Ardea’s post-transaction cash position to approximately $162 million, less cash used in operating activities during the first few weeks of January, he said. The company plans to release its 2010 earnings and file its annual financial report on March 11.

A number of analysts have had good things to say about Ardea since the company reported that the primary and key secondary endpoints of a Phase IIb study of RDEA594 in combination with the allopurinol were achieved, with highly statistically significant reductions in serum uric acid (sUA) and up to 89 percent of patients taking a combination of RDEA594 600 mg and allopurinol reaching target sUA. Allopurinol accounts for more than 90 percent of the unit sales of chronic gout prescription medications, the company said.

Jefferies & Co. analyst Thomas Wei wrote earlier this month that RDEA594. “could become the standard-of-care for second-line gout treatment.”

Wei added that “the next major strategic decision will be whether to partner RDEA594 or retain rights through Phase III trials, a decision which we expect the company to make within the next six to 12 months.”

Leerink Swann Research analyst Joseph Schwartz wrote during the first week of January that “RDEA594 is the front-runner in the race to becoming the next new oral gout drug.”

Jonathan Aschoff, an analyst for Brean Murray, estimated “the U.S. market for RDEA594, which only includes the 60 percent of allopurinol patients that do not adequately respond to allopurinol, as about a $3 billion opportunity.”

Last week Piper Jaffray & Co. analyst M. Ian Somaiya said in a company note that after meeting with Ardea management, “we believe that Ardea will conduct two Phase IIIs to ensure sufficient data, namely safety, for approval. Furthermore, we expect key efficacy endpoints, beyond sUA reductions, to include benefit in flare rate, thus allowing a broader label and potentially encompassing all gout patients.”

Nine months ago Ardea netted proceeds of about $77.1 million in a public offering of about 4 million shares. (See BioWorld Today, April 7, 2010.)

There are limited treatment options currently on the shelves for gout. Allopurinol has been the standard of care with Osaka, Japan-based Takeda Pharmaceutical Co. Ltd.’s xanthine oxidase inhibitor Uloric (febuxostat) gaining approval early in 2009. Savient Pharmaceuticals Inc., of East Brunswick, N.J., gained FDA approval in September 2010 for Krystexxa (pegloticase), a pegylated uric acid-specific enzyme for chronic refractory gout. (See BioWorld Today, Sept. 16, 2010.)

Beyond its gout program and MEK inhibitor partnership with Bayer, Ardea also has a Phase II-stage HIV program testing RDEA806, a non-nucleoside reverse transcriptase inhibitor.

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